Bioactivities of triterpenes and a sterol from Syzygium samarangense.

نویسندگان

  • Dennis D Raga
  • Candice Louise C Cheng
  • Kate Catherine Ilona C Lee
  • Wileen Zoe P Olaziman
  • Vernon Joseph A De Guzman
  • Chien-Chang Shen
  • Francisco C Franco
  • Consolacion Y Ragasa
چکیده

Cycloartenyl stearate (1a), lupenyl stearate (1b), sitosteryl stearate (1c), and 24-methylenecycloartanyl stearate (1d) (sample 1) from the air-dried leaves of Syzygium samarangense exhibited potent analgesic and anti-inflammatory activities at effective doses of 6.25 mg/kg body weight and 12.5 mg/kg body weight, respectively. Sample 1 also exhibited negligible toxicity on zebrafish embryonic tissues. There were incidences of mortality upon direct exposure of sample 1 to dechorionated embryos, but higher mortality and aberration were observed during intact chorion treatment.

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عنوان ژورنال:
  • Zeitschrift fur Naturforschung. C, Journal of biosciences

دوره 66 5-6  شماره 

صفحات  -

تاریخ انتشار 2011